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  • Dl‐3‐N‐butylphthalide promotes angiogenesis and upregulates sonic hedgehog expression after cerebral ischemia in rats

  • Multi-center, randomized, double-blind, double-simulation, controlled phase III clinical study of butylphthalide injection for acute cerebral infarction

    Studies have pointed out that Enbipu injection is effective and safe for the treatment of acute cerebral infarction. After intravenous administration on the 15th day, its efficacy is better than that of ozagrel sodium injection.

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  • A multicenter, randomized, double-blind, double-blind controlled study of dl-3-n-butylphenyl peptide soft capsule and aspirin-treated model of ischemic stroke

  • Systematic review of randomized controlled trials of butylphthalide in acute ischemic stroke

    The systematic review of butaphthalide was led by Professor Liu Ming from the West China Hospital of Sichuan University and included 21 trials (2123 patients). The meta-analysis showed the results: compared with placebo, aspirin, and combination of butylphthalein Compared with other therapies alone, the other treatments were significantly better than placebo, aspirin and other therapies, and there were significant statistical differences.

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  • Protective effects of dl-3n-butylphthalide against diffusebr

    In this study, a rat model of diffuse brain injury using the vertical impact method was established for SD rats. Immediately after the establishment of a diffuse brain injury model, 80 and 160 mg / kg butylphthalide was intraperitoneally injected, and the ultrastructural changes of the cerebral cortex were observed by electron microscopy. Cerebral blood flow was measured by laser Doppler flowmeter, vascular density was shown by tannic acid-chlorine staining, vascular permeability was estimated by Evans blue method, water content of brain tissue was measured by wet and dry method, and by exercise Functional and sensory function to test rat behavior. It was observed that ...

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  • DL-3-n-butylphthalide induced neuroprotection, regenerative

    A 2017 study published in Neurochemistry International with an impact factor of 3.385: Trials of traumatic brain injury (TBI) in mice were performed. After 21 days of NBP treatment, it was found that compared with the TBI control group, BDNF (brain Significantly increased expression of derived nerve growth factor), VEGF and eNOS, indicating that Enbipro promotes nerve cell regeneration and angiogenesis.

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  • Dl-3-n-Butylphthalide Treatment Enhances Hemodynamics and Am

    An article published in Frontiers in Aging Neuroscience with an impact factor of 4.504. A modified bilateral common carotid artery permanent occlusion method was used to establish a chronic cerebral hypoperfusion rat model, which was the first after bilateral common carotid artery ligation (BCCAO). Day, the administration was started via tail vein injection (dl-NBP 5mg / kg / d, course of treatment for 14 days). The results show that...

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  • 2016_Single copy-PEGylated liposomal doxorubicin expert consensus

  • Chinese expert consensus on PEGylated liposomal doxorubicin for recurrent ovarian cancer

  • Expert consensus on cognitive impairment management after stroke

    Consensus pointed out that research has confirmed that Enbipro can improve the cognitive function and overall function of patients with subcortical non-dementia vascular cognitive impairment, and has good safety and tolerance.

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  • Guidelines for the standardized management of neutropenia associated with tumor radiotherapy and chemotherapy

  • NCCN Clinical Practice Guidelines: Bone Marrow Growth Factor

  • NCCN Clinical Practice Guidelines: AIDS-Related Kaposi's Sarcoma

  • NCCN Clinical Practice Guidelines: Breast Cancer

  • NCCN Clinical Practice Guidelines: Ovarian Cancer Including Fallopian Tube Cancer and Primary Peritoneal Cancer